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T11942 |
MAP4K4-IN-3
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Compound 17 |
MAPK
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MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase. |
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T9191 |
XMD-17-51 Trifluoroacetate
|
XMD-17-51 Trifluoroacetate (1628614-50-5 free base) |
AMPK
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XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone compound that regulates protein kinases. |
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T60440 |
Antiviral agent 17
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Antiviral agent 17 (Compound 4) is an anti-infection agent that retains its strong antiviral effect in a human replicon assay with an EC50 of 0.015 μM. Antiviral agent 17 shows good antiviral activity against murine noro... |
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T61589 |
C-Fms-IN-13
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c-Fms
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c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent. |
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T60796 |
Cholesterol 24-hydroxylase-IN-1
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Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1) with IC50 of 8.5 nM that can cross blood-brain barrier [1]. |
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T30161 |
EN3356
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AS N001,ASN-001 |
P450
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EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and ant... |
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T64393 |
6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile
|
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Others
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6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilize... |
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T14083 |
Abaperidone
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Dopamine Receptor
,
5-HT Receptor
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Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound th... |
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T3142 |
Drostanolone Propionate
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Others
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Dromostanolone propionate (Drostanolone propionate) is a compound that has antitumor activity against breast carcinoma [1]. Dromostanolone propionate inhibits the uptake of oestradiol-17 by the tumor without apparent eff... |
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T11027 |
DHODH-IN-4
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|
Dehydrogenase
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DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity. |
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T20037 |
C.I. Direct Black 17
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Azine Fast Black D,CERN prima 17,Telon Fast Black PE,Diazol Black SD |
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C.I. Direct Black 17 is a compound of dye. |
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T60436 |
Tubulin inhibitor 17
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Tubulin inhibitor 17 (Compound 3b) is an inhibitor of tubulin polymerization (IC50 = 12.38 µM). Tubulin inhibitor 17 exhibits anticancer activities as well as induces cell apoptosis[1]. |
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T36525 |
IL-17 modulator 1 disodium
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IL-17 Modulator 1 (disodium) is a potent, orally active compound, known for its high efficacy in modulating IL-17. This compound is extensively utilized for researching various diseases such as psoriasis, ankylosing spon... |
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T40127 |
IL-17 modulator 3
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IL-17 modulator 3 (US20200247785A1) is a chemical compound that acts as an IL-17 modulator. It has potential applications in researching inflammation, cancer, and autoimmune diseases. |
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T82128 |
ICMT-IN-17
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ICMT-IN-17 (compound 52) serves as an ICMT inhibitor, exhibiting an IC50 value of 0.38 μM [1]. |
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T62369 |
Tubulin polymerization-IN-17
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Tubulin aggregation-IN-17 (compound 23g) is a potent inhibitor of tubulin aggregation. tubulin aggregation-IN-17 has a microtubulin-depolymerising effect, induces apoptosis and inhibits migration. tubulin aggregation-IN-... |
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T131621 |
17-hydroxy-17-methylandrost-4-ene-3,6-dione
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17-hydroxy-17-methylandrost-4-ene-3,6-dione is a useful organic compound for research related to life sciences and the catalog number is T131621. |
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T62501 |
PD-1/PD-L1-IN-17
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PD-1/PD-L1-IN-17 (Compound P20) is a potent PD-1/PD-L1 inhibitor (IC50: 26.8 nM). PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of PD-1/PD-L1 interactions. -17 has potential for cancer d... |
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T62466 |
HBV-IN-17
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HBV-IN-17 (compound 8) is a potent regulator of HBV capsid assembly (EC50: 511 nM). |
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T79005 |
6-Hydroxyluteolin
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6-Hydroxyluteolin (Compound 17), a flavonoid, exhibits inhibition of aldose reductase (AR) [1]. |
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T39712 |
RGLS4326
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RG4326,RGLS4326 |
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RGLS4326 (RG4326) is a short oligonucleotide inhibitor of microRNA-17 (miR-17), with a pioneering role in its class. This compound, with a research focus on autosomal dominant polycystic kidney disease (ADPKD), effective... |
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T63021 |
PTP1B-IN-17
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PTP1B-IN-17 (Compound 45) is a selective benzimidazole derivative with potential as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 30.2 μM).PTP1B-IN-17 can be used in the study of type 2 diabetes. |
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T131620 |
17-hydroxy-17-methylandrostane-3,6-dione
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17-hydroxy-17-methylandrostane-3,6-dione is a useful organic compound for research related to life sciences and the catalog number is T131620. |
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T62972 |
α-Glucosidase-IN-17
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α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory concentration (IC50) of 3.79 μM [1]. |
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T83027 |
Antioxidant agent-17
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Antioxidant agent-17 (compound 59) potently inhibits superoxide anion generation, exhibiting an IC50 value of 9.06 nM [1]. |
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T63410 |
CDK7-IN-17
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CDK7-IN-17 is a pyrimidine-derived compound and a potent inhibitor of CDK7. CDK7-IN-17 has shown research potential for a variety of cancers, particularly those with dysregulated transcription. |
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T78943 |
Syk-IN-7
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Syk
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Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1]. |
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T63082 |
IDO1-IN-19
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IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research. |
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T79660 |
SARS-CoV-2 3CLpro-IN-17
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SARS-CoV
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Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1]. |
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T16661 |
NH2-PEG5-C2-NH-Boc
|
PROTAC Linker 17 |
Others
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NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based compound utilized as a linker in the synthesis of PROTACs[1]. |
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T62981 |
KRAS inhibitor-17
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KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C (IC50: 3.37 μM). KRAS inhibitor-17 exhibits p-ERK inhibition with IC50 = 9.25 μM in MIA PaCA-2 cells and >33.3 μM in A549 cells. KRAS inhibitor-17 has t... |
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T62415 |
CBP/p300-IN-17
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CBP/p300-IN-17 (compound 7) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.18 μM) and LK2 H3K27 (IC50: 0.69 μM). |
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T40872 |
17-AEP-GA
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17-AEP-GA is a highly effective HSP90 antagonist compound that exhibits potent inhibition against the proliferation, survival, migration, and invasion of glioblastoma cells. Additionally, it demonstrates ADCs Toxin activ... |
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T61022 |
LSD1-IN-17
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LSD1-IN-17 (compound 5b) is a potent inhibitor of LSD1 that inhibits LSD1-CoREST, MAO-A and MAO-B, with IC 50 values of 0.005, 0.028, and 0.820 μM, respectively. LSD1-IN-17 exhibits cell growth arrest in prostate cancer ... |
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T61302 |
Anti-inflammatory agent 17
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Anti-inflammatory agent 17 an orally active anti-inflammatory agent, demonstrates potent efficacy in inhibiting the release of IL-6 and TNF-α without causing cytotoxicity in in vitro experiments. Furthermore, in vivo stu... |
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TJS1874 |
(+)-Lycoctonine
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Compound TJS1874 is a useful organic compound for research related to life sciences. The catalog number is TJS1874 and the CAS number is 26000-17-9. |
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T112208 |
Compound M754-2042
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Compound M754-2042 is a useful organic compound for research related to life sciences. The catalog number is T112208 and the CAS number is 2096209-17-3. |
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T125997 |
17-Methylparsonsianidine
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17-Methylparsonsianidine is a useful organic compound for research related to life sciences and the catalog number is T125997. |
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T124856 |
Estriol 17-sulfate
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Estriol 17-sulfate is a useful organic compound for research related to life sciences and the catalog number is T124856. |
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T61542 |
VEGFR-2-IN-17
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VEGFR-2-IN-17 (Compound 15a) is a highly potent inhibitor of Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2), with an IC50 value of 67.25 nM. This compound exhibits significant antitumor properties [1]. |
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T83013 |
Antitrypanosomal agent 17
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Parasite
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Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1]. |
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T131619 |
17-methylandrostane-3,6,17-triol
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17-methylandrostane-3,6,17-triol is a useful organic compound for research related to life sciences and the catalog number is T131619. |
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T75239 |
C-Myc inhibitor 10
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C-Myc Inhibitor 10 (compound 17), exhibiting enhanced cellular potency, benefits from increased permeability due to the methylation of the morpholine nitrogen [1]. |
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T61767 |
IRAK4-IN-17
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IRAK4-IN-17 (Compound 5) is a highly potent inhibitor of IRAK4, exhibiting an impressive IC50 value of 1.3 nM [1]. This compound is particularly valuable for research focused on large B-cell lymphoma (DLBCL) [1]. |
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T61613 |
SARS-CoV-2-IN-17
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SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to ... |
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T82770 |
CB2R agonist 2
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Cannabinoid Receptor
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CB2R agonist 2 (cis-17-para) is a CB2R agonist [1]. |
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T130150 |
17-Acetoxygrindelic acid
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17-Acetoxygrindelic acid is a useful organic compound for research related to life sciences and the catalog number is T130150. |
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T131617 |
17-hydroxypregn-4-ene-3,6-dione
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17-hydroxypregn-4-ene-3,6-dione is a useful organic compound for research related to life sciences and the catalog number is T131617. |
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T131436 |
Methyl 3-(acetyloxy)-15-oxoandrostane-17-carboxylate
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methyl 3-(acetyloxy)-15-oxoandrostane-17-carboxylate is a useful organic compound for research related to life sciences and the catalog number is T131436. |
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T61142 |
Antitubercular agent-17
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Antitubercular agent-17 (Compound 8a) is an efficacious antitubercular agent, demonstrating Minimum Inhibitory Concentration (MIC) values of 2 μg/ml against M. tuberculosis H37Rv, Spec. 192, and Spec 210, and 128 μg/ml a... |
